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Article

Molecular evolution and phylogenetic utility of the polyubiquitin locus in mammals and higher vertebrates.

Molecular phylogenetics and evolution - 1 Oct 1996

Vrana P B, Wheeler W C

Abstract excerpt

The product of ubiquitin genes is a small protein involved in intracellular sorting of other proteins. The locus consists of tandemly arrayed, uninterrupted copies of the gene. As several studies have noted, the Polyubiquitin locus is a model system for studying concerted evolution. While the protein is among the most conserved known, individual copies within an organism show variation in nucleotide sequence...

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PMID: 8899727
DOI: 10.1006/mpev.1996.0075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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