Article
Association of hepatosplenic schistosomiasis with HLA-DQB1*0201.
The Journal of infectious diseases - 1 Nov 1996
Secor W E, del Corral H, dos Reis M G, Ramos E A, Zimon A E, Matos E P, Reis E A, do Carmo T M, Hirayama K, David R A, David J R, Harn D A
Abstract excerpt
Major histocompatibility class II alleles of 351 persons living in an area endemic for Schistosoma mansoni in northeastern Brazil were characterized at three loci (DRB1, DQA1, and DQB1). Contingency analyses were used to compare allele frequencies with high egg excretion, proliferative response to schistosome soluble egg antigens (SEA), and occurrence of severe, biopsy-confirmed hepatosplenic disease. There were...
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