Saposin-like Proteins, a Multigene Family of<i>Schistosoma</i>Species, are Biomarkers for the Immunodiagnosis of Schistosomiasis Japonica

Abstract excerpt

BACKGROUND: One major obstacle to schistosomiasis prevention and control is the lack of accurate and sensitive diagnostic approaches, which are essential for planning, targeting, and evaluating disease control efforts. METHODS: Based on bioinformatics analysis, we identified a multigene family of saposin-like protein (SAPLP) in the schistosome genomes. Schistosoma japonicum SAPLPs (SjSAPLPs), including recently...

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