Strategy for distinguishing a new DQB1 allele (DQB1*0611) from the closely related DQB1*0602 allele via sequence specific PCR or direct DNA sequencing.

doi:10.1111/j.1399-0039.1996.tb02621.x

Article

Strategy for distinguishing a new DQB1 allele (DQB10611) from the closely related DQB10602 allele via sequence specific PCR or direct DNA sequencing.

Tissue antigens - 1 Sept 1996

Williams T M, Bassinger S, Moehlenkamp C, Wu J, Montoya G D, Griffith B B, McAuley J D, Goldman S, Maurer D H, Troup G M

Abstract excerpt

A novel DQ6 allele (DQB1*0611) was identified via direct DNA sequencing in an African-American donor for bone marrow transplantation. The allele was not suspected on the basis of a sequence specific PCR assay which instead indicated the presence of DQB1*0602. DQB1*0602 and DQB1*0611 differ in exon 2 only at codon 9 resulting in a tyrosine substitution for phenylalanine. A modification of current DQB1 sequence...

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Strategy for distinguishing a new DQB1 allele (DQB1*0611) from the closely related DQB1*0602 allele via sequence specific PCR or direct DNA sequencing.

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Strategy for distinguishing a new DQB1 allele (DQB10611) from the closely related DQB10602 allele via sequence specific PCR or direct DNA sequencing.