Article
APOE genotype and cardio-respiratory fitness interact to determine adiposity in 8-year-old children from the Tasmanian Infant Health Survey.
PloS one - 1 Jan 2011
Ellis Justine A, Ponsonby Anne-Louise, Pezic Angela, Williamson Elizabeth, Cochrane Jennifer A, Dickinson Joanne L, Dwyer Terence
Abstract excerpt
APOE plays a well established role in lipid metabolism. Animal model evidence suggests APOE may also be associated with adiposity, but this has not been thoroughly investigated in humans. We measured adiposity (BMI, truncal fat mass, waist circumference), physical activity (PA), cardiorespiratory fitness and APOE genotype (E2, E3, E4) in 292 8-year-old children from the Tasmanian Infant Health Survey (TIHS), an...
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