Aging mechanisms in fruit files.

Abstract excerpt

Genetic analysis of Drosophila has provided evidence in support of two proposed evolutionary genetic mechanisms of aging: mutation accumulation and antagonistic pleiotropy. Both mechanisms result from the lack of natural selection acting on old organisms. Analyses of large numbers of files have r...

Topics

• Aging
• Animals
• Biological Evolution
• Drosophila
• Female
• Genes, Insect
• Male
• Models, Genetic
• Mutation
• Oxidative Stress
• Superoxide Dismutase