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Article

Clinical strain of Staphylococcus aureus inactivates and causes efflux of macrolides

1 Apr 1996

Abstract excerpt

Searching through a collection of 124 Staphylococcus aureus clinical strains, we found one isolate, strain 01A1032, that inactivates 14- and 16-membered macrolides. The products of inactivation were purified from supernatant fluids of cultures exposed to erythromycin for 3 h and were found to be identical to products of inactivation from Escherichia coli strains that encode either an EreA or EreB esterase....

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PMID: 8849266
DOI: 10.1128/aac.40.4.992

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