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Article

Hepatitis C virus genotypes in the United States: epidemiology, pathogenicity, and response to interferon therapy. Collaborative Study Group.

Annals of internal medicine - 15 Oct 1996

Zein N N, Rakela J, Krawitt E L, Reddy K R, Tominaga T, Persing D H

Abstract excerpt

OBJECTIVE: To study 1) the geographic distribution and clinical significance of hepatitis C virus (HCV) genotypes in the United States and 2) the influence of HCV genotypes on response to interferon therapy. DESIGN: Hepatitis C virus genotype was determined in 179 stored serum samples obtained from patients who were positive for antibody to HCV and for HCV RNA by using polymerase chain reaction. SETTING: Tertiary...

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PMID: 8849147
DOI: 10.7326/0003-4819-125-8-199610150-00002

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