Effects of FK506 and cyclosporin A on proliferation, histamine release and phenotype of murine mast cells.

doi:10.1007/BF02505238

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Article

Effects of FK506 and cyclosporin A on proliferation, histamine release and phenotype of murine mast cells.

Archives of dermatological research - 1 Jul 1996

Toyota N, Hashimoto Y, Matsuo S, Kitamura Y, Iizuka H

Abstract excerpt

Using mouse peritoneal cavity mast cells, we investigated the effects of FK506 and cyclosporin A (CsA) on cell proliferation and histamine release induced by anti-IgE antibody, calcium ionophore (A23 187), or neuropeptide (substance P). Both FK506 and CsA inhibited cytokine-dependent mast cell pr...

Topics

Animals
Calcimycin
Cell Division
Cells, Cultured
Cyclosporine
Histamine Release
Immunoglobulin E
Immunosuppressive Agents
Ionophores
Mast Cells
Mice
Mice, Inbred Strains
Peritoneal Cavity
Phenotype
Substance P
Tacrolimus

Source

Open in PubMed

Identifiers

PMID: 8844128
DOI: 10.1007/BF02505238

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8844128-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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