Article
No evidence of association between structural polymorphism at the dopamine D3 receptor locus and alcoholism in the Japanese.
American journal of medical genetics - 26 Jul 1996
Higuchi S, Muramatsu T, Matsushita S, Murayama M
Abstract excerpt
Dopaminergic systems mediate reward mechanisms and are involved in reinforcing self-administration of dependence-forming substances, including alcohol. Studies have reported that polymorphisms of the dopamine D2 receptor, whose structure and function are similar to those of the dopamine D3 receptor, increase the susceptibility to alcoholism. These observations led to the examination of the possible association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.