Article
Different folding transition states may result in the same native structure.
Nature structural biology - 1 Oct 1996
Viguera A R, Serrano L, Wilmanns M
Abstract excerpt
The crystal structures of two circular permutants of the alpha-spectrin SH3 domain with new termini within the RT loop (S19-P20s) and the distal loop (N47-D48s) have been determined at 2.02 and 1.77 A resolution respectively. Both fold into the same three-dimensional structure as the wild-type SH3 domain except for the engineered loop that fuses the wild-type termini. The cleaved RT loop in S19-P20s loses nine...
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