Article
Influence of viraemia and genotype upon serological reactivity in screening assays for antibody to hepatitis C virus.
Journal of medical virology - 1 Feb 1996
Dhaliwal S K, Prescott L E, Dow B C, Davidson F, Brown H, Yap P L, Follett E A, Simmonds P
Abstract excerpt
Detection of antibody to recombinant proteins derived from hepatitis C virus (HCV) genotype 1 represents the principal method for diagnosis of HCV infection. A method was developed for quantifying antibody reactivity in two third-generation enzyme immunoassays (Ortho EIA 3.0 and Murex VK48), and the influence of viraemia, HCV genotype, and host factors such as age, gender, and risk group upon antibody levels were...
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