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Article

Comparative biochemical studies in fibroblasts from patients with different forms of Leigh syndrome.

Journal of inherited metabolic disease - 1 Jan 1996

Vazquez-Memije M E, Shanske S, Santorelli F M, Kranz-Eble P, Davidson E, DeVivo D C, DiMauro S

Abstract excerpt

We have compared respiratory chain enzyme activities, ATP synthesis, and ATP hydrolysis in cultured fibroblast mitochondria from patients with Leigh syndrome (LS) due to: (i) cytochrome oxidase (COX) deficiency (#6); (ii) pyruvate dehydrogenase complex (PDHC) deficiency (#4); and (iii) maternally...

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PMID: 8830176
DOI: 10.1007/BF01799347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8830176-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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