Article
Molecular evolution of aphthoviruses.
Virus genes - 1 Jan 1995
Domingo E, Mateu M G, Escarmís C, Martínez-Salas E, Andreu D, Giralt E, Verdaguer N, Fita I
Abstract excerpt
Aphthoviruses are an important group of animal pathogens. A combination of genetic and structural studies has revealed one of the main principles governing their evolution: severe limitations to variation imposed by functional and structural constraints, in conjunction with high mutation and recombination rates operating during genome replication. Evolution occurs by positive selection and random drift acting on...
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