Article
Cloning of an Aeromonas hydrophila type IV pilus biogenesis gene cluster: complementation of pilus assembly functions and characterization of a type IV leader peptidase/N-methyltransferase required for extracellular protein secretion.
Molecular microbiology - 1 Feb 1996
Pepe C M, Eklund M W, Strom M S
Abstract excerpt
Aeromonas hydrophila secretes several extracellular proteins that are associated with virulence including an enterotoxin, a protease, and the hole-forming toxin, aerolysin. These degradative enzymes and toxins are exported by a conserved pathway found in many Gram-negative bacteria. In Pseudomonas aeruginosa this export pathway and type IV pilus biogenesis are dependent on the product of the pilD gene. PilD is a...
Topics
- Aeromonas hydrophila
- Amino Acid Sequence
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- Cloning, Molecular
- Endopeptidases
- Fimbriae Proteins
- Fimbriae, Bacterial
- Genes, Bacterial
- Genetic Complementation Test
- Methyltransferases