The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.

Abstract excerpt

The Pseudomonas aeruginosa pilG gene, encoding a protein which is involved in pilus production, was cloned by phenotypic complementation of a unique, pilus-defective mutant of strain PAO1. This mutant, designated FA2, although resistant to the pilus-specific phage D3112 was sensitive to the pilus-specific phages B3 and F116L. In spite of the unusual phage sensitivity pattern, FA2 lacked the ability to produce...

Topics

• Amino Acid Sequence
• Bacterial Proteins
• Base Sequence
• Cloning, Molecular
• DNA, Bacterial
• Escherichia coli
• Escherichia coli Proteins
• Fimbriae Proteins
• Fimbriae, Bacterial
• Genetic Complementation Test