Article
Catabolite repression resistance of gnt operon expression in Bacillus subtilis conferred by mutation of His-15, the site of phosphoenolpyruvate-dependent phosphorylation of the phosphocarrier protein HPr.
Journal of bacteriology - 1 Sept 1996
Reizer J, Bergstedt U, Galinier A, Küster E, Saier M H, Hillen W, Steinmetz M, Deutscher J
Abstract excerpt
Carbon catabolite repression of the gnt operon of Bacillus subtilis is mediated by the catabolite control protein CcpA and by HPr, a phosphocarrier protein of the phosphotransferase system. ATP-dependent phosphorylation of HPr at Ser-46 is required for carbon catabolite repression as ptsH1 mutant...
Topics
- Bacillus subtilis
- Bacterial Proteins
- DNA-Binding Proteins
- Gene Conversion
- Gene Expression Regulation, Bacterial
- Histidine
- Mutation
- Operon
- Phosphoenolpyruvate
- Phosphoenolpyruvate Sugar Phosphotransferase System
- Phosphorylation
- Protein Binding
- Repressor Proteins