Article
A new mutation affecting FRQ-less rhythms in the circadian system of Neurospora crassa.
PLoS genetics - 1 Jun 2011
Li Sanshu, Motavaze Kamyar, Kafes Elizabeth, Suntharalingam Sujiththa, Lakin-Thomas Patricia
Abstract excerpt
We are using the fungus Neurospora crassa as a model organism to study the circadian system of eukaryotes. Although the FRQ/WCC feedback loop is said to be central to the circadian system in Neurospora, rhythms can still be seen under many conditions in FRQ-less (frq knockout) strains. To try to identify components of the FRQ-less oscillator (FLO), we carried out a mutagenesis screen in a FRQ-less strain and...
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