Article
Genetic fine mapping of the gene for recessive Stargardt disease.
Human genetics - 1 Oct 1996
Hoyng C B, Poppelaars F, van de Pol T J, Kremer H, Pinckers A J, Deutman A F, Cremers F P
Abstract excerpt
Stargardt disease (STGD) is one of the most frequent causes of macular degeneration in childhood. Linkage analysis in families with recessive STGD has recently shown genetic homogeneity and a location of the underlying gene at 1p22-p21 in a 4-cM interval. Haplotype analysis in seven Dutch STGD fa...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Color Perception
- Female
- Genes, Recessive
- Genetic Markers
- Humans
- Lod Score
- Macular Degeneration
- Male
- Middle Aged
- Netherlands
- Pedigree
- Polymorphism, Genetic