Fibrinogen Matsumoto II: gamma 308 Asn-->Lys (AAT-->AAG) mutation associated with bleeding tendency.

doi:10.1046/j.1365-2141.1996.d01-1833.x

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Article

Fibrinogen Matsumoto II: gamma 308 Asn-->Lys (AAT-->AAG) mutation associated with bleeding tendency.

British journal of haematology - 1 Sept 1996

Okumura N, Furihata K, Terasawa F, Ishikawa S, Ueno I, Katsuyama T

Abstract excerpt

Fibrinogen Matsumoto II is a hereditary dysfibrinogenaemia identified in a woman with Basedow's disease and a bleeding tendency. Coagulation tests of the patient's plasma revealed a prolonged thrombin time and a decreased fibrinogen level determined by functional method. Release of fibrinopeptide...

Topics

Afibrinogenemia
Base Sequence
Blood Coagulation Disorders
Female
Fibrinogens, Abnormal
Humans
Middle Aged
Molecular Sequence Data
Mutation
Postpartum Hemorrhage
Pregnancy

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