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Article

Variability of genotype-specific penetrance probabilities in the calculation of risk support intervals.

Genetic epidemiology - 1 Jan 1995

Leal S M, Ott J

Abstract excerpt

Previously, a maximum likelihood method was described to construct a support interval for the risk. This method is extended to incorporate genotype specific penetrance probabilities in the calculation of a risk support interval. As an empirical example, the support interval for the risk is calculated for a member of a published breast-ovarian cancer kindred.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8788022
DOI: 10.1002/gepi.1370120655
PMCID: PMC6141013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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