Article
Red cell abnormalities in hereditary spherocytosis: relevance to diagnosis and understanding of the variable expression of clinical severity.
The Journal of laboratory and clinical medicine - 1 Sept 1996
Cynober T, Mohandas N, Tchernia G
Abstract excerpt
Marked variations in the clinical manifestations of hereditary spherocytosis (HS) have long been recognized. However, neither the molecular nor the cellular basis for this variable expression has been fully delineated. To better define the cellular basis for variable expression of the disease, we...
Topics
- Adolescent
- Adult
- Aged
- Anemia
- Child
- Child, Preschool
- Erythrocyte Deformability
- Erythrocyte Indices
- Erythrocyte Membrane
- Erythrocytes
- Humans
- Infant
- Middle Aged
- Phenotype
- Spherocytosis, Hereditary
- Splenectomy