Article
Properties of xanthine dehydrogenase variants from rosy mutant strains of Drosophila melanogaster and their relevance to the enzyme's structure and mechanism.
European journal of biochemistry - 1 Aug 1996
Doyle W A, Burke J F, Chovnick A, Dutton F L, Whittle J R, Bray R C
Abstract excerpt
Xanthine dehydrogenase, a molybdenum, iron-sulfur flavoenzyme encoded in the fruit fly Drosophila melanogaster by the rosy gene, has been characterised both from the wild-type and mutant files. Enzyme assays, using a variety of different oxidising and reducing substrates were supplemented by limi...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Coenzymes
- Conserved Sequence
- Cross Reactions
- Drosophila melanogaster
- Enzyme Activation
- Genetic Variation
- Kinetics
- Metalloproteins
- Molecular Sequence Data
- Molybdenum Cofactors
- Mutagenesis, Site-Directed
- Mutation
- NAD
- Oxidation-Reduction
- Pteridines