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Article

Assembly properties of neurofilament light chain Ser55 mutants in transfected mammalian cells.

Journal of neurochemistry - 1 Mar 1996

Gibb B J, Robertson J, Miller C C

Abstract excerpt

Ser55 within the head domain of neurofilament light chain (NF-L) is transiently phosphorylated by protein kinase A, and phosphorylation of this residue is thought to regulate assembly of neurofilaments. To understand how Ser55 phosphorylation influences NF-L assembly, wild-type and mutant NF-L genes in which Ser55 was mutated to alanine, so as to prevent phosphorylation, or to aspartate, so as to mimic permanent...

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Identifiers

PMID: 8769898
DOI: 10.1046/j.1471-4159.1996.66031306.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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