Hb Aubenas [beta 62(B8)Glu-->Gly]: a new variant normally synthesized, affecting the same codon as in Hb E.

doi:10.3109/03630269609027916

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Article

Hb Aubenas [beta 62(B8)Glu-->Gly]: a new variant normally synthesized, affecting the same codon as in Hb E.

Hemoglobin - 1 May 1996

Lacan P, Francina A, Promé D, Delaunay J, Galactéros F, Wajcman H

Abstract excerpt

Hb Aubenas [beta 26(B8)Glu-->Gly] is a mildly unstable variant that was found in a French family without hematological or clinical features. The structural abnormality was determined by protein chemistry methods, including tandem mass spectrometry, and was confirmed by Apa I digestion of a polyme...

Topics

Adolescent
Codon
Electrophoresis, Agar Gel
Female
Globins
Hemoglobin E
Hemoglobins, Abnormal
Humans
Mutation
Polymorphism, Restriction Fragment Length

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