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Article

First trimester serum screening for down's syndrome

1 Dec 1995

Abstract excerpt

Screening for Down's Syndrome has been shown to be effective at 10 weeks of pregnancy. A multicentre study (the first trimester serum screening study) has shown that there are two biochemical markers of choice at this time in pregnancy, namely pregnancy associated placental protein A (PAPP-A) and the free beta-sub-unit of human chorionic gonadotrophin (free beta-hCG). When used together with maternal age these...

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PMID: 8710764
DOI: 10.1002/pd.1970151305

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