Article
Ductular reaction after submassive necrosis in humans. Special emphasis on analysis of ductular hepatocytes.
The American journal of pathology - 1 Aug 1996
Demetris A J, Seaberg E C, Wennerberg A, Ionellie J, Michalopoulos G
Abstract excerpt
The ductular reaction to acute submassive necrosis was studied in human livers removed at the time of orthotopic liver transplantation. Single, double, and triple immunohistochemical labeling in combination with morphometry was used to analyze the phenotype and proliferative and apoptotic rates o...
Topics
- Adult
- Aged
- Apoptosis
- Bile Ducts, Intrahepatic
- Cell Compartmentation
- Cell Count
- Collagenases
- DNA
- DNA Nucleotidylexotransferase
- Epithelium
- Female
- Humans
- Immunohistochemistry
- Ki-67 Antigen
- Liver Transplantation
- Male
- Matrix Metalloproteinase 9
- Middle Aged