Article
Dimorphism and haploid fruiting in Cryptococcus neoformans: association with the alpha-mating type.
Proceedings of the National Academy of Sciences of the United States of America - 9 Jul 1996
Wickes B L, Mayorga M E, Edman U, Edman J C
Abstract excerpt
Cryptococcus neoformans is a major opportunistic fungal pathogen in AIDS and other immunosuppressed patients. We have shown that wild-type haploid C. neoformans can develop an extensive hyphal phase under appropriate conditions. Hyphae produced under these conditions are monokaryotic, possess unfused clamp connections, and develop basidia with viable basidiospores. The ability to undergo this transition is...
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