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Article

Role of the Yersinia pestis hemin storage (hms) locus in the transmission of plague by fleas.

Science (New York, N.Y.) - 19 Jul 1996

Hinnebusch B J, Perry R D, Schwan T G

Abstract excerpt

Yersinia pestis, the cause of bubonic plague, is transmitted by the bites of infected fleas. Biological transmission of plague depends on blockage of the foregut of the flea by a mass of plague bacilli. Blockage was found to be dependent on the hemin storage (hms) locus. Yersinia pestis hms mutants established long-term infection of the flea's midgut but failed to colonize the proventriculus, the site in the...

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Identifiers

PMID: 8662526
DOI: 10.1126/science.273.5273.367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 8 closest

Role of the Yersinia pestis hemin storage (hms) locus in the transmission of plague by fleas.PMID 8662526Read ↗

The haemin storage (Hms+) phenotype of Yersinia pestis is not essential for the pathogenesis of bubonic plague in mammals.Semantic proximity Read ↗

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Identification and cloning of a hemin storage locus involved in the pigmentation phenotype of Yersinia pestis.Semantic proximity Read ↗

Characterization of a hemin-storage locus of Yersinia pestis.Semantic proximity Read ↗

Temperature regulation of the hemin storage (Hms+) phenotype of Yersinia pestis is posttranscriptional.Semantic proximity Read ↗

Sequence and genetic analysis of the hemin storage (hms) system of Yersinia pestis.Semantic proximity Read ↗

Molecular characterization of the hemin uptake locus (hmu) from Yersinia pestis and analysis of hmu mutants for hemin and hemoprotein utilization.Semantic proximity Read ↗

Silencing urease: a key evolutionary step that facilitated the adaptation of Yersinia pestis to the flea-borne transmission route.Semantic proximity Read ↗

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