Article
Genotyping of PCR-based polymorphisms and linkage-disequilibrium analysis at the NF1 locus.
American journal of human genetics - 1 Jul 1996
Purandare S M, Cawthon R, Nelson L M, Sawada S, Watkins W S, Ward K, Jorde L B, Viskochil D H
Abstract excerpt
Six polymorphisms across the NF1 gene have been adapted for genotyping through application of PCR-based assays. Three exon-based polymorphisms--at positions 702, 2034, and 10647 in the NF1 cDNA--were genotyped by mutagenically separated PCR (MS-PCR). A fourth polymorphism, DV1.9, is an L1 insertion element in intron 30, and the other two polymorphisms, GXAlu and EVI-20, are short tandem repeats in intron 27b. All...
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