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Novel Human Vascular Endothelial Growth Factor Genes VEGF-B and VEGF-C Localize to Chromosomes 11q13 and 4q34, Respectively

15 Mar 1996

Abstract excerpt

BACKGROUND: Vascular endothelial growth factor (VEGF) is an important regulator of endothelial cell proliferation, migration, and permeability during embryonic vasculogenesis as well as in physiological and pathological angiogenesis. The recently isolated VEGF-B and VEGF-C cDNAs encode novel growth factor genes of the VEGF family. METHODS AND RESULTS: Southern blotting and polymerase chain reaction analysis of...

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PMID: 8653826
DOI: 10.1161/01.cir.93.6.1079

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