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The Leishmania Genome Comprises 36 Chromosomes Conserved Across Widely Divergent Human Pathogenic Species

1 May 1996

Abstract excerpt

All the physical linkage groups constituting the genome of Leishmania infantum have been identified for the first time by hybridization of specific DNA probes to pulsed field gradient-separated chromosomes. The numerous co-migrating chromosomes were individualised using the distinctive size polymorphisms which occur among strains of the L. infantum/L. donovani complex as a tool. A total of 244 probes, consisting...

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PMID: 8649987
DOI: 10.1093/nar/24.9.1688

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