Article
Recruitment of wild-type and recombinant adeno-associated virus into adenovirus replication centers.
Journal of virology - 1 Mar 1996
Weitzman M D, Fisher K J, Wilson J M
Abstract excerpt
Replication of a human parvovirus, adeno-associated virus (AAV), is facilitated by coinfection with adeno-virus to provide essential helper functions. We have used the techniques of in situ hybridization and immunocytochemistry to characterize the localization of AAV replication within infected cells, Previous studies have shown that adenovirus establishes foci called replication centers within the nucleus, where...
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