Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Green Fluorescent Protein-Tagged Adeno-Associated Virus Particles Allow the Study of Cytosolic and Nuclear Trafficking

1 Sept 2005

Abstract excerpt

To allow the direct visualization of viral trafficking, we genetically incorporated enhanced green fluorescent protein (GFP) into the adeno-associated virus (AAV) capsid by replacement of wild-type VP2 by GFP-VP2 fusion proteins. High-titer virus progeny was obtained and used to elucidate the process of nuclear entry. In the absence of adenovirus 5 (Ad5), nuclear translocation of AAV capsids was a slow and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16140755
DOI: 10.1128/jvi.79.18.11776-11787.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Green Fluorescent Protein-Tagged Adeno-Associated Virus Particles Allow the Study of Cytosolic and Nuclear TraffickingPMID 16140755Read ↗

Infection of Purified Nuclei by Adeno-associated Virus 2Semantic proximity Read ↗

Recombinant Adeno-Associated Virus Utilizes Host Cell Nuclear Import Machinery To Enter the NucleusSemantic proximity Read ↗

Fluorescent Virions: Dynamic Tracking of the Pathway of Adenoviral Gene Transfer Vectors in Living CellsSemantic proximity Read ↗

Adeno-associated virus type 5 exploits two different entry pathways in human embryo fibroblastsSemantic proximity Read ↗

Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.Semantic proximity Read ↗

Impaired Intracellular Trafficking of Adeno-Associated Virus Type 2 Vectors Limits Efficient Transduction of Murine FibroblastsSemantic proximity Read ↗

Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directionsSemantic proximity Read ↗

Fluorescent protein tagging of adenoviral proteins pV and pIX reveals ‘late virion accumulation compartment’Semantic proximity Read ↗

Recruitment of wild-type and recombinant adeno-associated virus into adenovirus replication centers.Semantic proximity Read ↗

Adenovirus – a blueprint for gene deliverySemantic proximity Read ↗

Adeno-associated virus 9 (AAV9) viral proteins VP1, VP2, and membrane-associated accessory protein (MAAP) differentially influence in vivo transgene expressionSemantic proximity Read ↗

Separate Basic Region Motifs within the Adeno-Associated Virus Capsid Proteins Are Essential for Infectivity and AssemblySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.