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Article

Kinetics of Intratumoral Immune Cell Activation During Chemoradiation for Cervical Cancer.

International journal of radiation oncology, biology, physics - 1 Nov 2018

Dorta-Estremera Stephanie, Colbert Lauren E, Nookala Sita S, Yanamandra Ananta V, Yang Guojun, Delgado Andrea, Mikkelson Megan, Eifel Patricia, Jhingran Anuja, Lilie Lin L, Welsh James, Schmeler Kathleen, Sastry Jagannadha K, Klopp Ann

Abstract excerpt

PURPOSE: Radiation therapy has direct cytotoxic effects on tumor-infiltrating lymphocytes, but it also has immune stimulatory effects that increase immune cell infiltration. The dynamics of these competing effects on immune cells at the site of the tumor are poorly characterized during chemoradiation treatment (CRT) because of the difficulty of obtaining consecutive tumor biopsies. We used a minimally invasive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30017792
DOI: 10.1016/j.ijrobp.2018.06.404
PMCID: PMC6721616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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