Article
Earthworm leukocytes that are not phagocytic and cross-react with several human epitopes can kill human tumor cell lines.
Experimental cell research - 10 Apr 1996
Cossarizza A, Cooper E L, Suzuki M M, Salvioli S, Capri M, Gri G, Quaglino D, Franceschi C
Abstract excerpt
Earthworm coelomocytes (leukocytes) effect cytotoxicity at significantly high levels against the NK-sensitive, human tumor cell line, K562, and the NK-resistant targets (U937, BSM, CEM). By cytofluorimetric analyses using mouse anti-human monoclonal antibodies and by morphological evaluations, two types of coelomocytes were identified: (1) small (8-11 micron) electron-dense cells (SC): CD11a+, CD45RA+, CD45RO+,...
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