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Article

Cranial desmoid tumor associated with homozygous inactivation of the adenomatous polyposis coli gene in a 2-year-old girl with familial adenomatous polyposis.

Cancer - 1 Mar 1996

de Silva D C, Wright M F, Stevenson D A, Clark C, Gray E S, Holmes J D, Dean J C, Haites N E, Dunlop M G

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis (FAP) is a dominantly inherited disorder characterized by the presence of more than 100 adenomatous polyps in the colon and rectum starting in the second decade of life. FAP is associated with extra colonic manifestations, including desmoid tumors. METHO...

Topics

Adenomatous Polyposis Coli
Adult
Alleles
Base Sequence
Child, Preschool
DNA, Neoplasm
Female
Desmoid Tumors
Forehead
Gene Expression Regulation, Neoplastic
Genes, APC
Head and Neck Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homozygote

Humans

Male

Molecular Sequence Data

Mutation

Source

Identifiers

PMID: 8608492

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8608492-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Cranial desmoid tumor associated with homozygous inactivation of the adenomatous polyposis coli gene in a 2-year-old girl with familial adenomatous polyposis.PMID 8608492Read ↗

Desmoid Tumors in Familial Adenomatous PolyposisSemantic proximity Read ↗

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