Article
A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 1995
Puliti A, Prehu M O, Simon-Chazottes D, Ferkdadji L, Peuchmaur M, Goossens M, Guénet J L
Abstract excerpt
Dominant megacolon (Dom) is one of four mutations in the mouse that can produce a phenotype similar to Hirschsprung disease in human. The Dom gene product is not known, and no candidate region has been defined for a possible human homolog. In this publication we report mapping the Dom locus with high definition, using several intra-and interspecific crosses and a set of 16 Chr 15-specific microsatellites flanking...
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