A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus.

doi:10.1007/BF00539000

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Article

A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 1995

Puliti A, Prehu M O, Simon-Chazottes D, Ferkdadji L, Peuchmaur M, Goossens M, Guénet J L

Abstract excerpt

Dominant megacolon (Dom) is one of four mutations in the mouse that can produce a phenotype similar to Hirschsprung disease in human. The Dom gene product is not known, and no candidate region has been defined for a possible human homolog. In this publication we report mapping the Dom locus with...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Female
Hirschsprung Disease
Male
Mice
Mice, Mutant Strains
Microsatellite Repeats
Mutation

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