Article
A collection of tri- and tetranucleotide repeat markers used to generate high quality, high resolution human genome-wide linkage maps.
Human molecular genetics - 1 Oct 1995
Sheffield V C, Weber J L, Buetow K H, Murray J C, Even D A, Wiles K, Gastier J M, Pulido J C, Yandava C, Sunden S L
Abstract excerpt
We report a collection of tri- and tetranucleotide repeat sequence polymorphic markers used to construct genome-wide human linkage maps. Using a strategy of marker selection to create libraries highly enriched for the presence of specific tandem repeat elements, we have developed over 2000 high h...
Topics
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human
- DNA Primers
- Family
- Genetic Carrier Screening
- Genetic Linkage
- Genetic Markers
- Genome, Human
- Genotype
- Humans
- Polymerase Chain Reaction