Article
Family studies of type II CD36 deficient subjects: linkage of a CD36 allele to a platelet-specific mRNA expression defect(s) causing type II CD36 deficiency.
Thrombosis and haemostasis - 1 Aug 1995
Kashiwagi H, Tomiyama Y, Kosugi S, Shiraga M, Lipsky R H, Nagao N, Kanakura Y, Kurata Y, Matsuzawa Y
Abstract excerpt
We performed family studies with type II CD36 deficiency. In the Mi. Y family, the proband (YII.1) and his brother (YII.2) displayed a type II deficient phenotype. In the mother (YI.2), binding of the anti-CD36 monoclonal antibody, OKM5, to both platelets and monocytes was reduced as compared to CD36 positive control cells. In the father (YI.1), while OKM5 binding to his platelets was reduced, that of his...
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