Reduced uptake of nickel by a nickel resistant strain of Candida utilis.

Abstract excerpt

A nickel resistant strain of the yeast Candida utilis was obtained by selection of spontaneous mutants on solid medium containing 3 mM Ni2+. In time-course experiments, non-growing suspensions of the mutant strain took up approximately 50% less nickel than the parent strain over 30 min incubation in MES buffer plus glucose at pH 5.5. Efflux of nickel from either strain was negligible. Uptake was reduced by...

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