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Article

Malignant transformation of HPV 16-immortalized human endocervical cells by cigarette smoke condensate and characterization of multistage carcinogenesis

26 Jan 1996

Abstract excerpt

A number of epidemiological studies indicate that cigarette smokers are at increased risk of developing cervical cancer. However, convincing biological evidence is lacking. This report examines the biological and cellular role of human papillomavirus (HPV) type 16 and cigarette smoke in multistage cervical carcinogenesis. Two lines of HPV 16-immortalized human endocervical cells (HEN-16 and HEN-16-2) generated...

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Identifiers

PMID: 8575855
DOI: 10.1002/(sici)1097-0215(19960126)65:3<338::aid-ijc11>3.0.co;2-6

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