Article
Molecular markers in cancer diagnosis.
Journal of the National Cancer Institute. Monographs - 1 Jan 1995
Sidransky D
Abstract excerpt
Clonal genetic alterations are a hallmark of human cancer pathogenesis. These genetic alterations may include specific gene mutations that drive the cancer process or phenotypic changes such as microsatellite instability that may be caused by specific genetic events. Identification of clonal cell populations that share a specific genetic alteration is virtually synonymous with the detection of cancer. These...
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