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Article

Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection

1 Jan 1996

Abstract excerpt

The human cytomegalovirus (HCMV) DNA polymerase gene (UL54; also called pol) is a prototypical early gene in that expression is mandatory for viral DNA replication. Recently, we have identified the major regulatory element in the UL54 promoter responsive to the major immediate early (MIE) proteins (UL122 and UL123) (J.A. Kerry, M.A. Priddy, and R. M. Stenberg, J. Virol. 68:4167-4176, 1994). Mutation of this...

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Identifiers

PMID: 8523551
DOI: 10.1128/jvi.70.1.373-382.1996

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