Article
Mechanism for inhibition of influenza virus RNA polymerase activity by matrix protein.
Journal of virology - 1 Jan 1996
Watanabe K, Handa H, Mizumoto K, Nagata K
Abstract excerpt
Influenza virus M1 protein has been shown to inhibit the transcription catalyzed by viral ribonucleoprotein complexes isolated from virions. Here, this inhibition mechanism was studied with the recombinant M1 protein purified from Escherichia coli expressing it from cDNA. RNA mobility shift assay...
Topics
- Base Sequence
- Binding Sites
- DNA Primers
- DNA-Directed RNA Polymerases
- Enzyme Inhibitors
- Influenza A virus
- Molecular Sequence Data
- Mutation
- RNA
- Recombinant Fusion Proteins
- Transcription, Genetic
- Viral Matrix Proteins