Article
The protease-sensitive loop of the vesicular stomatitis virus matrix protein is involved in virus assembly and protein translation.
Virology - 20 Jul 2011
Mire Chad E, Whitt Michael A
Abstract excerpt
To study the contribution of the protease-sensitive loop of the VSV M protein in virus assembly we recovered recombinant VSV (rVSV) with mutations in this region and examined virus replication. Mutations in the highly conserved LXD motif (aa 123-125) resulted in reduced virion budding, reduced virus titers and enhanced M protein exchange with M-ribonucleocapsid complexes (M-RNPs), suggesting that the mutant M...
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