Transthyretin gene mutations in British and French patients with amyloid neuropathy.

doi:10.1136/jnnp.56.6.694

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Article

Transthyretin gene mutations in British and French patients with amyloid neuropathy.

Journal of neurology, neurosurgery, and psychiatry - 1 Jun 1993

Bhatia K, Reilly M, Adams D, Davis M B, Hawkes C H, Thomas P K, Said G, Harding A E

Abstract excerpt

Five patients, two British and three French, with late onset amyloid neuropathy were found to have mutations of the transthyretin (TTR) gene associated with the Portuguese and German types of familial amyloid polyneuropathy. Familial amyloid polyneuropathy is rare in the United Kingdom and has no...

Topics

Aged
Amyloid
Amyloidosis
Base Sequence
DNA Mutational Analysis
Female
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Nervous System Diseases
Prealbumin

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