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Article

Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis.

15 May 1993

Abstract excerpt

Erythropoietin regulates the proliferation and differentiation of erythroid precursor cells. Its effect is mediated by the erythropoietin receptor (EPOR), a member of a large family of cytokine receptors. The EPOR gene has recently been cloned, sequenced, and characterized. As shown experimentally, its intracellular C-terminal part contains a domain exerting negative control on erythropoiesis. Here we describe a...

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Identifiers

PMID: 8506290
DOI: 10.1073/pnas.90.10.4495

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Source receipt: pubmed, retrieved 7 Sept 2026.

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