Article
The need for more accurate and timely diagnosis in Fanconi anemia: a report from the International Fanconi Anemia Registry.
Pediatrics - 1 Jun 1993
Giampietro P F, Adler-Brecher B, Verlander P C, Pavlakis S G, Davis J G, Auerbach A D
Abstract excerpt
OBJECTIVE: The objective of this study was to address the need for early diagnosis of Fanconi anemia (FA), an autosomal recessive chromosomal instability syndrome characterized by a unique cellular hypersensitivity to DNA cross-linking agents, such as diepoxybutane, and by a high risk of malignancies. METHODS: We analyzed data from 370 FA patients enrolled in the American Registry of the International FA...
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