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Article

Variation in Course of Hepatitis E in Experimentally Infected Cynomolgus Monkeys

1 Jun 1993

Abstract excerpt

Five cynomolgus monkeys (Macaca fascicularis) developed hepatitis after inoculation with a prototype strain of hepatitis E virus (HEV) from Pakistan. Although all 5 monkeys displayed liver enzyme elevations, viremia, virus secretion in feces, and seroconversion, two different patterns of these parameters were observed. For 4 monkeys, increased alanine aminotransferase (ALT) activity was first observed on days...

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PMID: 8501318
DOI: 10.1093/infdis/167.6.1302

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